A trio of Mysterios are running rampant through the school that Peter teaches at. Francis Klum is determined to kill Spider-Man to avenge his brother. Daniel Beckhart is looking to put Klum down and prove that he's the real Mysterio. Spider-Man finds himself caught between the both of them, as he tries to get as many civilians to safety as he can.Flash Thompson manages to lead a bunch of kids to safety outside the school, before turning around to try to help Spidey, and Miss Arrow, a teacher who got separated from him in the chaos.And the third Mysterio? He's the original, Quentin Beck. He's returned from death at the bidding of some master. He's convinced that there's more to Miss Arrow than she's let on, and his masters want her to try to keep Peter employed at the school.