This 48-page one-shot serves as a comprehensive recap of the first twelve issues of the Astonishing X-Men series, written by Joss Whedon and illustrated by John Cassaday. Rather than reprinting the original comics, it provides a narrative summary of key events and character developments.

The issue covers major story arcs, including the introduction of a "cure" for mutation, the return of Colossus, and the emergence of the Danger Room as a sentient entity. It also highlights the team's battles against formidable adversaries like Ord and the challenges posed by the Breakworld prophecy.