Cortex, the mysterious chronal assassin terminating mutants and their ancestors in the 21st century is revealed to be one of Madrox' duplicates. And now that he's lost his mental hold on M and Longshot, he's faced with Siryn and a very angry Monet St. Croix.

Eighty years in the future, Jamie and Layla have brought Dr. Doom back to Atlantic City in an effort to stop the 'Doomlock' technology he invented that's allowing Cortex to change the past. But Cyclops isn't happy to have even an ancient, half-senile Dr. Doom so close. And Anthony Falcone, the man behind the President's stand against mutants is none too happy with the man who helped guide him into his position... Damian Tryp!