This issue is part of the "Season of the Witch" arc and serves as a tie-in to the House of M event. In this storyline, Psylocke (Betsy Braddock), Marvel Girl (Rachel Summers), and Nocturne (Talia Wagner) confront the Marauders in an abandoned church in England. The trio battles to prevent the destruction of the universe, facing formidable adversaries like Caliban and T-Rex. The narrative delves into themes of identity and reality, reflecting the altered world brought about by the House of M event.

This issue is notable for introducing Chris Bachalo as the new regular artist, bringing a distinctive visual style to the series.