This issue concludes the "Destruction's Daughter" arc, focusing on Cassandra Cain's journey to uncover her lineage. The narrative reaches a climax as Batgirl aids Mr. Freeze in reviving his wife, Nora. However, the resurrection takes a dark turn when Nora, transformed by the Lazarus Pit's effects, becomes the powerful entity known as Lazara. She blames Mr. Freeze for her transformation and unleashes her newfound powers, leading to a confrontation that tests Batgirl's resolve and sets the stage for future challenges.

This issue is part of the Batgirl: Destruction's Daughter trade paperback, which collects issues #65–73 of the series. The collection was published on September 20, 2006, and delves deeper into Cassandra Cain's personal struggles and her confrontations with figures from her past.