The Wasp has been turned into a weapon of mass destruction, and it's up to Earth's heroes to prevent the cataclysm. Even when this is over and done with, there are ramifications that must be dealt with. The Skrulls attacked and hurt Earth like nobody ever has, and they did so on Tony Stark's watch. What happens to him and to S.H.I.E.L.D. is more severe than many would have predicted.