This issue kicks off the “Supreme Apocalypse” storyline, setting the stage for one of the title’s most intense arcs.

A mysterious, powerful force begins manipulating time and reality around Supreme, destabilizing both Earth and the wider cosmic order. Supreme returns from deep space sensing something is terribly wrong — entire cities are vanishing and reappearing, and familiar enemies seem to be converging toward a single purpose. Meanwhile, Probe, Supreme’s daughter from the future, arrives with a dire warning: a future timeline is collapsing, and Supreme is at its center.

Elsewhere, a secret council of Supreme’s greatest foes — including Darkthornn, Optilux, and covert operatives within the government — form a loose alliance, believing that destroying Supreme is the only way to survive what’s coming. Supreme begins to experience strange memory lapses and vision fragments, hinting that the very nature of his existence may be unraveling.

This issue is primarily setup, but it layers heavy foreshadowing and brings several long-running plot threads (Supreme’s identity crisis, the looming cosmic threat, and Earth’s vulnerability) together into one explosive direction, leading directly into the Apocalypse arc’s escalation.