The Fantastic Four face mounting danger in Siberia as Reed, Ben, and Johnny launch a full assault to rescue Sue from Ivan Kragoff's secret Russian facility. Reed uncovers evidence that Kragoff’s “Ghost” program uses unstable dimensional-phase technology capable of rendering its subjects intangible — but mentally unstable and increasingly violent.

Meanwhile, Sue continues resisting Kragoff’s psychological manipulation while learning the disturbing truth about the prior Ghost test subjects, whose failed transformations haunt the base. The FF must navigate phasing assassins, environmental traps, and Kragoff’s unstable science as the confrontation escalates.

By the end of the issue, the Ghost technology spirals out of control — threatening to collapse the entire facility and everyone inside.